Donna
Hi, My husband has had Crohn's for about 20 years now. He is on Pentasa also. He has never had a reaction. He has had 2 surgeries and has removed most of his small intestines. He has been in remission for the last 6 years, and is doing great. He also takes B12 injections once a month and a multivitamin. Let me know if I can be of any help to you. Take care. Donna